| 1 | Vertex Pharmaceuticals IncorporatedVRTX | $134.2B | $528.90 |
| 2 | Regeneron Pharmaceuticals, Inc.REGN | $83.5B | $810.31 |
| 3 | Moderna, Inc.MRNA | $55.7B | $140.33 |
| 4 | Revolution Medicines, Inc.RVMD | $44.1B | $207.32 |
| 5 | Alnylam Pharmaceuticals, Inc.ALNY | $34.8B | $260.10 |
| 6 | Roivant Sciences Ltd.ROIV | $30.0B | $41.48 |
| 7 | Insmed IncorporatedINSM | $27.1B | $124.89 |
| 8 | Incyte CorporationINCY | $25.2B | $124.40 |
| 9 | United Therapeutics CorporationUTHR | $21.1B | $497.97 |
| 10 | Neurocrine Biosciences, Inc.NBIX | $15.6B | $155.13 |
| 11 | Jazz Pharmaceuticals plcJAZZ | $15.1B | $240.07 |
| 12 | BridgeBio Pharma, Inc.BBIO | $14.6B | $74.76 |
| 13 | Exelixis, Inc.EXEL | $14.5B | $57.67 |
| 14 | Summit Therapeutics Inc.SMMT | $13.8B | $17.28 |
| 15 | Halozyme Therapeutics, Inc.HALO | $12.8B | $108.31 |
| 16 | BioMarin Pharmaceutical Inc.BMRN | $12.5B | $64.63 |
| 17 | Madrigal Pharmaceuticals, Inc.MDGL | $12.3B | $534.16 |
| 18 | Arrowhead Pharmaceuticals, Inc.ARWR | $12.0B | $85.11 |
| 19 | Bio-Techne CorporationTECH | $11.3B | $72.31 |
| 20 | Axsome Therapeutics, Inc.AXSM | $10.7B | $207.82 |
| 21 | Krystal Biotech, Inc.KRYS | $10.4B | $351.26 |
| 22 | Praxis Precision Medicines, Inc.PRAX | $9.8B | $352.48 |
| 23 | Kymera Therapeutics, Inc.KYMR | $9.6B | $116.47 |
| 24 | Ionis Pharmaceuticals, Inc.IONS | $9.4B | $56.71 |
| 25 | Protagonist Therapeutics, Inc.PTGX | $9.4B | $145.94 |
| 26 | Cytokinetics, IncorporatedCYTK | $9.4B | $75.35 |
| 27 | Nuvalent, Inc.NUVL | $9.1B | $123.96 |
| 28 | Crinetics Pharmaceuticals, Inc.CRNX | $9.0B | $84.95 |
| 29 | Vaxcyte, Inc.PCVX | $8.7B | $60.36 |
| 30 | ImmunityBio, Inc.IBRX | $8.7B | $8.29 |
| 31 | TG Therapeutics, Inc.TGTX | $8.5B | $55.74 |
| 32 | Apogee Therapeutics, Inc.APGE | $8.4B | $135.07 |
| 33 | 10x Genomics, Inc.TXG | $8.3B | $65.60 |
| 34 | Immunovant, Inc.IMVT | $8.2B | $39.57 |
| 35 | Twist Bioscience CorporationTWST | $8.0B | $128.06 |
| 36 | Spyre Therapeutics, Inc.SYRE | $7.9B | $90.79 |
| 37 | Caris Life Sciences, Inc.CAI | $7.0B | $24.82 |
| 38 | Rhythm Pharmaceuticals, Inc.RYTM | $7.0B | $101.80 |
| 39 | Scholar Rock Holding CorporationSRRK | $6.9B | $57.42 |
| 40 | CG Oncology Inc.CGON | $6.5B | $73.40 |
| 41 | Travere Therapeutics, Inc.TVTX | $6.1B | $66.07 |
| 42 | Dianthus Therapeutics, Inc.DNTH | $6.1B | $109.13 |
| 43 | Mirum Pharmaceuticals, Inc.MIRM | $6.1B | $99.53 |
| 44 | Cogent Biosciences, Inc.COGT | $6.0B | $35.28 |
| 45 | Ligand Pharmaceuticals IncorporatedLGND | $5.8B | $288.83 |
| 46 | Xenon Pharmaceuticals Inc.XENE | $5.8B | $59.55 |
| 47 | PTC Therapeutics, Inc.PTCT | $5.7B | $68.81 |
| 48 | Oruka Therapeutics, Inc.ORKA | $5.7B | $94.31 |
| 49 | Erasca, Inc.ERAS | $5.7B | $16.28 |
| 50 | CRISPR Therapeutics AGCRSP | $5.3B | $54.78 |
| 51 | Apellis Pharmaceuticals, Inc.APLS | $5.3B | $41.03 |
| 52 | Definium Therapeutics, Inc.DFTX | $5.1B | $38.23 |
| 53 | ACADIA Pharmaceuticals Inc.ACAD | $4.7B | $27.58 |
| 54 | Edgewise Therapeutics, Inc.EWTX | $4.7B | $43.82 |
| 55 | Parabilis Medicines, Inc.PBLS | $4.6B | $39.77 |
| 56 | Celcuity Inc.CELC | $4.5B | $93.02 |
| 57 | Veradermics, IncorporatedMANE | $4.3B | $103.83 |
| 58 | Enliven Therapeutics, Inc.ELVN | $4.2B | $59.37 |
| 59 | Relay Therapeutics, Inc.RLAY | $4.2B | $19.11 |
| 60 | Viking Therapeutics, Inc.VKTX | $3.9B | $33.68 |
| 61 | Adaptive Biotechnologies CorporationADPT | $3.9B | $24.34 |
| 62 | Iovance Biotherapeutics, Inc.IOVA | $3.9B | $8.70 |
| 63 | Catalyst Pharmaceuticals, Inc.CPRX | $3.9B | $31.49 |
| 64 | Dyne Therapeutics, Inc.DYN | $3.8B | $20.31 |
| 65 | Amylyx Pharmaceuticals, Inc.AMLX | $3.8B | $33.88 |
| 66 | Tarsus Pharmaceuticals, Inc.TARS | $3.8B | $87.22 |
| 67 | Tango Therapeutics, Inc.TNGX | $3.7B | $22.70 |
| 68 | IDEAYA Biosciences, Inc.IDYA | $3.7B | $38.84 |
| 69 | Arcus Biosciences, Inc.RCUS | $3.7B | $29.06 |
| 70 | Denali Therapeutics Inc.DNLI | $3.5B | $22.08 |
| 71 | Arcutis Biotherapeutics, Inc.ARQT | $3.1B | $24.39 |
| 72 | MBX Biosciences, Inc. Common StockMBX | $3.0B | $62.99 |
| 73 | Disc Medicine, Inc.IRON | $3.0B | $76.84 |
| 74 | Beam Therapeutics Inc.BEAM | $2.8B | $26.83 |
| 75 | Mineralys Therapeutics, Inc.MLYS | $2.7B | $31.12 |
| 76 | Nurix Therapeutics, Inc.NRIX | $2.7B | $26.13 |
| 77 | Viridian Therapeutics, Inc.VRDN | $2.6B | $23.17 |
| 78 | Celldex Therapeutics, Inc.CLDX | $2.6B | $39.12 |
| 79 | SELLAS Life Sciences Group, Inc.SLS | $2.6B | $13.96 |
| 80 | Immunome, Inc.IMNM | $2.6B | $26.81 |
| 81 | Vera Therapeutics, Inc.VERA | $2.5B | $35.28 |
| 82 | Ocular Therapeutix, Inc.OCUL | $2.5B | $11.37 |
| 83 | Precigen, Inc.PGEN | $2.4B | $6.87 |
| 84 | Harmony Biosciences Holdings, Inc.HRMY | $2.4B | $42.07 |
| 85 | Trevi Therapeutics, Inc.TRVI | $2.4B | $16.82 |
| 86 | BioCryst Pharmaceuticals, Inc.BCRX | $2.3B | $9.07 |
| 87 | Nuvation Bio Inc.NUVB | $2.3B | $6.61 |
| 88 | Biohaven Ltd.BHVN | $2.2B | $14.72 |
| 89 | ADMA Biologics, Inc.ADMA | $2.2B | $9.54 |
| 90 | Sarepta Therapeutics, Inc.SRPT | $2.2B | $20.94 |
| 91 | Rapport Therapeutics, Inc. Common StockRAPP | $2.2B | $46.09 |
| 92 | Kodiak Sciences Inc.KOD | $2.2B | $35.07 |
| 93 | Palvella Therapeutics, Inc.PVLA | $2.2B | $152.28 |
| 94 | Nektar TherapeuticsNKTR | $2.2B | $75.44 |
| 95 | UroGen Pharma Ltd.URGN | $2.1B | $43.82 |
| 96 | Kailera Therapeutics, Inc.KLRA | $2.1B | $16.43 |
| 97 | Zenas BioPharma, Inc.ZBIO | $2.1B | $33.05 |
| 98 | Hemab Therapeutics Holdings, Inc. Common StockCOAG | $2.1B | $44.57 |
| 99 | Alamar Biosciences, Inc.ALMR | $2.1B | $29.95 |
| 100 | Zymeworks Inc.ZYME | $2.1B | $28.11 |
| 101 | Aurinia Pharmaceuticals Inc.AUPH | $2.1B | $16.07 |
| 102 | Generate Biomedicines, Inc.GENB | $2.0B | $15.90 |
| 103 | Agios Pharmaceuticals, Inc.AGIO | $2.0B | $33.55 |
| 104 | Vericel CorporationVCEL | $2.0B | $39.08 |
| 105 | Maravai LifeSciences Holdings, Inc.MRVI | $2.0B | $7.19 |
| 106 | Stoke Therapeutics, Inc.STOK | $1.9B | $30.05 |
| 107 | Kardigan, Inc.KARD | $1.9B | $21.60 |
| 108 | Vir Biotechnology, Inc.VIR | $1.9B | $11.18 |
| 109 | Xencor, Inc.XNCR | $1.9B | $25.33 |
| 110 | Recursion Pharmaceuticals, Inc.RXRX | $1.8B | $3.44 |
| 111 | Damora Therapeutics, Inc.DMRA | $1.8B | $29.17 |
| 112 | Intellia Therapeutics, Inc.NTLA | $1.8B | $12.74 |
| 113 | Syndax Pharmaceuticals, Inc.SNDX | $1.8B | $19.94 |
| 114 | Taysha Gene Therapies, Inc.TSHA | $1.8B | $5.48 |
| 115 | Septerna IncSEPN | $1.7B | $37.37 |
| 116 | Inhibrx Biosciences Inc.INBX | $1.7B | $114.34 |
| 117 | AnaptysBio, Inc.ANAB | $1.7B | $56.60 |
| 118 | Novavax, Inc.NVAX | $1.7B | $10.19 |
| 119 | Avalyn Pharma Inc. Common StockAVLN | $1.7B | $37.62 |
| 120 | Fortrea Holdings Inc.FTRE | $1.6B | $17.06 |
| 121 | Tyra Biosciences, Inc.TYRA | $1.6B | $26.73 |
| 122 | Forte Biosciences, Inc.FBRX | $1.6B | $76.99 |
| 123 | Innoviva, Inc.INVA | $1.6B | $21.34 |
| 124 | Bicara Therapeutics Inc. Common StockBCAX | $1.6B | $23.71 |
| 125 | Absci CorporationABSI | $1.5B | $8.91 |
| 126 | Ultragenyx Pharmaceutical Inc.RARE | $1.5B | $14.88 |
| 127 | Xeris Biopharma Holdings, Inc.XERS | $1.5B | $8.48 |
| 128 | Maze Therapeutics, Inc.MAZE | $1.5B | $26.37 |
| 129 | First Tracks Biotherapeutics IncTRAX | $1.5B | $41.80 |
| 130 | KalVista Pharmaceuticals, Inc.KALV | $1.4B | $27.00 |
| 131 | LB Pharmaceuticals Inc Common StockLBRX | $1.4B | $49.39 |
| 132 | ArriVent BioPharma, Inc.AVBP | $1.4B | $30.28 |
| 133 | Omeros CorporationOMER | $1.4B | $19.12 |
| 134 | Vor Biopharma Inc.VOR | $1.4B | $25.10 |
| 135 | Aktis Oncology, Inc.AKTS | $1.3B | $25.02 |
| 136 | Cullinan Therapeutics, Inc.CGEM | $1.3B | $21.69 |
| 137 | MannKind CorporationMNKD | $1.3B | $4.16 |
| 138 | ORIC Pharmaceuticals, Inc.ORIC | $1.3B | $12.62 |
| 139 | Alumis Inc.ALMS | $1.3B | $10.58 |
| 140 | Odyssey Therapeutics, Inc.ODTX | $1.3B | $26.97 |
| 141 | Seaport Therapeutics, Inc. Common StockSPTX | $1.3B | $24.06 |
| 142 | Alto Neuroscience, Inc.ANRO | $1.3B | $35.81 |
| 143 | MeiraGTx Holdings plcMGTX | $1.3B | $13.53 |
| 144 | Replimune Group, Inc.REPL | $1.2B | $14.77 |
| 145 | Janux Therapeutics, Inc.JANX | $1.2B | $20.04 |
| 146 | Monte Rosa Therapeutics, Inc.GLUE | $1.2B | $14.27 |
| 147 | Jade Biosciences, Inc.JBIO | $1.2B | $19.45 |
| 148 | Corvus Pharmaceuticals, Inc.CRVS | $1.2B | $13.93 |
| 149 | Apnimed, Inc.APMD | $1.1B | $28.79 |
| 150 | Savara Inc.SVRA | $1.1B | $5.53 |
| 151 | Kura Oncology, Inc.KURA | $1.1B | $12.52 |
| 152 | Avalo Therapeutics, Inc.AVTX | $1.0B | $19.71 |
| 153 | Arbutus Biopharma CorpABUS | $1.0B | $5.18 |
| 154 | Lexicon Pharmaceuticals, Inc.LXRX | $990.6M | $2.23 |
| 155 | Solid Biosciences Inc.SLDB | $977.6M | $9.93 |
| 156 | Geron CorporationGERN | $968.7M | $1.51 |
| 157 | Wave Life Sciences Ltd.WVE | $967.5M | $4.91 |
| 158 | SpyGlass Pharma, Inc. Common StockSGP | $966.9M | $28.92 |
| 159 | Sana Biotechnology, Inc.SANA | $960.1M | $3.45 |
| 160 | Olema Pharmaceuticals, Inc.OLMA | $959.5M | $10.99 |
| 161 | Design Therapeutics, Inc.DSGN | $951.2M | $15.23 |
| 162 | Ardelyx, Inc.ARDX | $931.3M | $3.77 |
| 163 | Candel Therapeutics, Inc.CADL | $923.2M | $12.60 |
| 164 | Climb Bio, Inc.CLYM | $910.5M | $15.90 |
| 165 | Theravance Biopharma IncTBPH | $884.2M | $17.06 |
| 166 | Rigel Pharmaceuticals, Inc.RIGL | $876.4M | $47.37 |
| 167 | Aclaris Therapeutics, Inc.ACRS | $846.4M | $6.06 |
| 168 | Achieve Life Sciences, Inc.ACHV | $804.8M | $7.84 |
| 169 | Gyre Therapeutics, Inc.GYRE | $799.4M | $7.17 |
| 170 | CytomX Therapeutics, Inc.CTMX | $794.6M | $3.65 |
| 171 | Monopar Therapeutics Inc.MNPR | $766.2M | $114.38 |
| 172 | Annexon, Inc.ANNX | $765.1M | $4.67 |
| 173 | 4D Molecular Therapeutics, Inc.FDMT | $764.8M | $14.63 |
| 174 | Phathom Pharmaceuticals, Inc.PHAT | $762.9M | $9.43 |
| 175 | Aura Biosciences, Inc.AURA | $761.3M | $7.36 |
| 176 | Crescent Biopharma, Inc.CBIO | $760.0M | $20.46 |
| 177 | Zevra Therapeutics, Inc.ZVRA | $749.3M | $12.68 |
| 178 | Immix Biopharma, Inc.IMMX | $720.8M | $13.25 |
| 179 | Verastem, Inc.VSTM | $710.0M | $8.08 |
| 180 | BridgeBio Oncology Therapeutics Inc.BBOT | $709.7M | $8.86 |
| 181 | Assembly Biosciences, Inc.ASMB | $699.2M | $35.28 |
| 182 | MiMedx Group, Inc.MDXG | $680.7M | $4.67 |
| 183 | Esperion Therapeutics, Inc.ESPR | $661.1M | $3.18 |
| 184 | Bright Minds Biosciences Inc.DRUG | $654.9M | $66.91 |
| 185 | Altimmune, Inc.ALT | $653.4M | $3.36 |
| 186 | Prime Medicine, Inc.PRME | $643.0M | $3.56 |
| 187 | Allogene Therapeutics, Inc.ALLO | $642.0M | $1.86 |
| 188 | CorMedix Inc.CRMD | $641.7M | $8.18 |
| 189 | Nuvectis Pharma, Inc.NVCT | $636.6M | $23.99 |
| 190 | OmniAb, Inc.OABI | $614.7M | $4.24 |
| 191 | Neurogene Inc.NGNE | $602.5M | $38.13 |
| 192 | Contineum Therapeutics, Inc.CTNM | $599.7M | $15.94 |
| 193 | MapLight Therapeutics, Inc.MPLT | $592.0M | $13.95 |
| 194 | Shattuck Labs, Inc.STTK | $587.4M | $6.50 |
| 195 | Arvinas, Inc.ARVN | $585.9M | $9.08 |
| 196 | Eikon Therapeutics, Inc. Common StockEIKN | $579.8M | $10.71 |
| 197 | Tectonic Therapeutic, Inc.TECX | $573.6M | $30.40 |
| 198 | ARS Pharmaceuticals, Inc.SPRY | $535.2M | $5.39 |
| 199 | Cabaletta Bio, Inc.CABA | $533.2M | $3.27 |
| 200 | Artiva Biotherapeutics, Inc.ARTV | $531.9M | $10.88 |
| 201 | Capricor Therapeutics, Inc.CAPR | $521.0M | $9.06 |
| 202 | Ovid Therapeutics Inc.OVID | $513.3M | $2.75 |
| 203 | Scribe Therapeutics Inc.SCTX | $507.1M | $31.34 |
| 204 | XOMA Royalty Corp.XOMA | $503.8M | $40.17 |
| 205 | Prothena Corporation plcPRTA | $499.4M | $9.54 |
| 206 | Kyverna Therapeutics, Inc.KYTX | $490.6M | $8.07 |
| 207 | Puma Biotechnology, Inc.PBYI | $477.9M | $9.39 |
| 208 | Evommune, Inc.EVMN | $474.7M | $13.08 |
| 209 | Editas Medicine, Inc.EDIT | $465.0M | $3.03 |
| 210 | Atea Pharmaceuticals, Inc.AVIR | $454.6M | $5.68 |
| 211 | Ginkgo Bioworks Holdings, Inc.DNA | $453.4M | $6.94 |
| 212 | REGENXBIO Inc.RGNX | $452.9M | $8.76 |
| 213 | Ocugen, Inc.OCGN | $451.0M | $1.33 |
| 214 | Relmada Therapeutics, Inc.RLMD | $445.8M | $4.25 |
| 215 | Arcturus Therapeutics Holdings Inc.ARCT | $444.3M | $15.63 |
| 216 | Benitec Biopharma Inc.BNTC | $437.2M | $12.73 |
| 217 | Fennec Pharmaceuticals Inc.FENC | $432.5M | $12.45 |
| 218 | Rezolute, Inc.RZLT | $423.7M | $4.40 |
| 219 | Larimar Therapeutics, Inc.LRMR | $423.3M | $4.08 |
| 220 | Rocket Pharmaceuticals, Inc.RCKT | $405.1M | $3.71 |
| 221 | Compass Therapeutics, Inc.CMPX | $398.0M | $2.21 |
| 222 | Enanta Pharmaceuticals, Inc.ENTA | $392.6M | $13.50 |
| 223 | C4 Therapeutics, Inc.CCCC | $392.5M | $3.55 |
| 224 | EyePoint Pharmaceuticals, Inc.EYPT | $382.3M | $4.56 |
| 225 | Turn Therapeutics Inc.TTRX | $377.1M | $12.66 |
| 226 | Lexeo Therapeutics, Inc. Common StockLXEO | $373.8M | $4.76 |
| 227 | Opus Genetics, Inc.IRD | $358.3M | $4.34 |
| 228 | Keros Therapeutics, Inc.KROS | $357.4M | $11.17 |
| 229 | BioAge Labs Inc.BIOA | $353.7M | $9.40 |
| 230 | Sagimet Biosciences Inc.SGMT | $349.0M | $10.71 |
| 231 | Q32 Bio Inc.QTTB | $347.9M | $11.69 |
| 232 | Upstream Bio, Inc.UPB | $336.9M | $6.19 |
| 233 | Abeona Therapeutics Inc.ABEO | $333.4M | $5.85 |
| 234 | Lyell Immunopharma, Inc.LYEL | $331.5M | $13.53 |
| 235 | X4 Pharmaceuticals, Inc.XFOR | $330.6M | $3.51 |
| 236 | SAB Biotherapeutics, Inc.SABS | $330.3M | $3.63 |
| 237 | Sionna Therapeutics, Inc.SION | $329.6M | $7.30 |
| 238 | Orchestra BioMed Holdings, Inc.OBIO | $325.2M | $5.43 |
| 239 | Inhibikase Therapeutics, Inc.IKT | $320.8M | $2.43 |
| 240 | Vanda Pharmaceuticals Inc.VNDA | $320.5M | $5.33 |
| 241 | Agenus Inc.AGEN | $309.4M | $7.43 |
| 242 | Prelude Therapeutics IncorporatedPRLD | $301.7M | $5.30 |
| 243 | Entrada Therapeutics, Inc.TRDA | $291.9M | $7.52 |
| 244 | Fulcrum Therapeutics, Inc.FULC | $291.5M | $3.82 |
| 245 | Fate Therapeutics, Inc.FATE | $291.4M | $2.50 |
| 246 | Zentalis Pharmaceuticals, Inc.ZNTL | $286.9M | $4.03 |
| 247 | Foghorn Therapeutics Inc.FHTX | $283.6M | $4.83 |
| 248 | Akebia Therapeutics, Inc.AKBA | $276.3M | $1.03 |
| 249 | MacroGenics, Inc.MGNX | $274.6M | $4.32 |
| 250 | Alector, Inc.ALEC | $274.2M | $2.47 |
| 251 | Galectin Therapeutics Inc.GALT | $272.6M | $4.14 |
| 252 | Lineage Cell Therapeutics, Inc.LCTX | $271.7M | $1.09 |
| 253 | ALX Oncology Holdings Inc.ALXO | $269.1M | $2.00 |
| 254 | Anavex Life Sciences Corp.AVXL | $264.1M | $2.85 |
| 255 | Cartesian Therapeutics, Inc.RNAC | $263.0M | $8.95 |
| 256 | Whitehawk Therapeutics IncWHWK | $250.3M | $4.39 |
| 257 | Niagen Bioscience IncNAGE | $246.9M | $3.10 |
| 258 | Pyxis Oncology, Inc.PYXS | $246.5M | $3.89 |
| 259 | Invivyd, Inc.IVVD | $243.3M | $0.83 |
| 260 | Greenwich LifeSciences, Inc.GLSI | $233.4M | $15.90 |
| 261 | Neumora Therapeutics, Inc. Common StockNMRA | $231.6M | $1.25 |
| 262 | Nkarta, Inc.NKTX | $231.1M | $3.23 |
| 263 | Acumen Pharmaceuticals, Inc.ABOS | $228.2M | $3.16 |
| 264 | Eledon Pharmaceuticals, Inc.ELDN | $226.2M | $2.93 |
| 265 | PepGen Inc.PEPG | $222.0M | $3.21 |
| 266 | Protara Therapeutics, Inc.TARA | $218.6M | $3.89 |
| 267 | AN2 Therapeutics, Inc.ANTX | $215.4M | $5.98 |
| 268 | Armata Pharmaceuticals, Inc.ARMP | $213.7M | $5.82 |
| 269 | Coherus Oncology, Inc.CHRS | $211.7M | $1.37 |
| 270 | Tonix Pharmaceuticals Holding Corp.TNXP | $209.8M | $13.16 |
| 271 | Voyager Therapeutics, Inc.VYGR | $205.4M | $3.40 |
| 272 | Minerva Neurosciences, Inc.NERV | $203.6M | $4.37 |
| 273 | Corbus Pharmaceuticals Holdings, Inc.CRBP | $196.3M | $10.60 |
| 274 | Atrium Therapeutics, Inc.RNA | $194.1M | $11.35 |
| 275 | Sutro Biopharma, Inc.STRO | $184.8M | $19.10 |
| 276 | Century Therapeutics, Inc.IPSC | $179.2M | $2.07 |
| 277 | Immunic, Inc.IMUX | $173.5M | $12.74 |
| 278 | Immuneering CorporationIMRX | $173.5M | $4.78 |
| 279 | MediWound Ltd.MDWD | $172.6M | $13.44 |
| 280 | Canton Strategic Holdings IncCNTN | $172.0M | $2.23 |
| 281 | LENZ Therapeutics, Inc.LENZ | $167.1M | $5.33 |
| 282 | ADC Therapeutics S.A.ADCT | $165.3M | $1.30 |
| 283 | Spruce Biosciences, Inc.SPRB | $162.6M | $59.09 |
| 284 | Surrozen, Inc.SRZN | $154.6M | $20.68 |
| 285 | Codexis, Inc.CDXS | $153.8M | $1.43 |
| 286 | Caribou Biosciences, Inc.CRBU | $152.7M | $1.54 |
| 287 | Equillium, Inc.EQ | $152.4M | $2.41 |
| 288 | Tenaya Therapeutics, Inc.TNYA | $144.0M | $0.66 |
| 289 | Biomea Fusion, Inc.BMEA | $139.5M | $1.93 |
| 290 | OnKure Therapeutics, Inc.OKUR | $137.7M | $3.40 |
| 291 | MaxCyte, Inc.MXCT | $136.6M | $1.28 |
| 292 | TuHURA Biosciences, Inc.HURA | $135.0M | $2.12 |
| 293 | Korro Bio, Inc.KRRO | $134.5M | $13.51 |
| 294 | Unicycive Therapeutics, Inc.UNCY | $134.3M | $5.03 |
| 295 | Cibus, Inc.CBUS | $122.9M | $1.61 |
| 296 | Black Diamond Therapeutics, Inc.BDTX | $120.3M | $2.10 |
| 297 | Outlook Therapeutics, Inc.OTLK | $119.8M | $0.64 |
| 298 | Nautilus Biotechnolgy, Inc.NAUT | $118.1M | $0.93 |
| 299 | Vivani Medical, Inc.VANI | $116.8M | $1.36 |
| 300 | Aardvark Therapeutics, Inc. Common StockAARD | $116.6M | $5.33 |
| 301 | Genelux CorporationGNLX | $113.9M | $2.54 |
| 302 | Fractyl Health, Inc.GUTS | $108.7M | $0.69 |
| 303 | Coya Therapeutics, Inc.COYA | $108.1M | $4.61 |
| 304 | Seer, Inc.SEER | $107.2M | $1.95 |
| 305 | Neonc Technologies Holdings, Inc.NTHI | $105.5M | $4.07 |
| 306 | Humacyte, Inc.HUMA | $99.9M | $0.59 |
| 307 | Polaryx Therapeutics, Inc. Common StockPLYX | $99.7M | $2.00 |
| 308 | RenovoRx, Inc.RNXT | $99.1M | $2.20 |
| 309 | Anixa Biosciences, Inc.ANIX | $98.7M | $2.90 |
| 310 | Aldeyra TheALDX | $89.3M | $1.48 |
| 311 | Spero Therapeutics, Inc.SPRO | $70.1M | $1.21 |
| 312 | Tenax Therapeutics, Inc.TENX | $51.5M | $1.94 |
| 313 | Karyopharm Therapeutics Inc.KPTI | $40.6M | $1.79 |
