Alnylam Pharmaceuticals, Inc.· ALNY

🇺🇸 US · LargeBroad USNASDAQ

HealthcareBiotechnologyWebsite

Price: $219.00
Day: -0.60%
Mkt Cap: $29.30B
52W Range: $197.81 – $495.55
Volume: 3.04M
Beta: 0.27

D55D FrameworkQuarterly Data

Holdings Analysis

Insider activity, institutional flows, and fund ownership.

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Alnylam Pharmaceuticals, Inc.

ALNY|Healthcare|Biotechnology

Current price: $219

Smart Money

Dimension 5 of 5

Insider Activity, Q2 2026

Latest scored quarter, net flow, and top transactions by value

Net dollar flow-$2.4M

Net share flow-7.7K

Purchases0 ($0)

Sales19 ($2.4M)

Top Notable Transactions

Insider

Type

Value

Date

Greenstreet Yvonne

Sale

$7.7M

May 30

Greenstreet Yvonne

Sale

$5.9M

Jun 2

BONNEY MICHAEL W

Sale

$5.1M

Aug 18

Institutional Ownership, Q1 2026

Ownership share, position changes, share flow, and top holders

Ownership98.4%

13F share flow-20.8%

Investors holding821

+525 adding-431 reducing

103

422

264

167

New 103Inc 422Red 264Closed 167

Top Institutional Holders

Institution

Value

Change

FMR LLC

$4.8B

-8.3%

CAPITAL WORLD INVESTORS

$3.6B

-34.1%

BLACKROCK, INC.

$3.5B

-0.5%

CAPITAL RESEARCH GLOBAL INVESTORS

$3.1B

+38.9%

ETF & Mutual Fund Activity, Q2 2026

Latest meaningful quarter: fund-by-fund buying / unchanged / selling

Funds reporting208

Total shares held38.9M

Share flow-3.9%

71 buying48 selling

Buying 71Unchanged 89Selling 48

Top Fund Holders

Fund

Weight

Change

PARNASSUS FUNDS

49.0K

5.07%

See the complete picture

The full 5D Framework: Business Quality · Peer Comparison · Valuation · Analyst Sentiment · Smart Money

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Generated August 5, 2026

For educational purposes only. Not financial advice. Data may be delayed or incomplete.

Smart Money Sentiment

ALNY Smart Money Sentiment Score

A weighted 1-5 sentiment score across three smart money signals.

Smart Money

3.4/5

Neutral

Weighted across 3 components

Component Breakdown (3 of 3 available)

Insider Activity

40% weight

+25

Institutional Flow

50% weight

+12

Fund Flow

10% weight

+25

Overall Smart Money sentiment of 3.4/5 (Neutral) based on a weighted combination of 3 components. Insider activity uses a relative-baseline comparison against the stock's own history; institutional flow tracks position momentum and 13F share changes; fund flow measures ETF / mutual-fund buying vs selling. Higher scores indicate stronger bullish sentiment from professional investors.Last updated August 4, 2026.

Insider Trading Activity

Insider trading analysis comparing the latest quarter against the stock's own historical baseline.

Insider Activity for ALNY

Net insider share flow by quarter (C-suite & director purchases minus sales)

Bullish Signal

Insider selling eased in Q2 2026

19 sales totaling $2.4M (7.7K shares)

Share volume is well below the historical pace (0.1x average), insiders are holding more

Buying seen in 1 of 7 quarters

Selling has increased for 4 straight quarters

Notable Recent Transactions, ALNY

Top 8 highest-value recent insider trades

Greenstreet Yvonne

Director

Sell

25,469 shares at $304.00

May 30, 2025$7.74M

Greenstreet Yvonne

Director

Sell

19,297 shares at $306.00

Jun 2, 2025$5.90M

BONNEY MICHAEL W

Director

Sell

11,250 shares at $450.00

Aug 18, 2025$5.06M

Fitzgerald Kevin Joseph

Officer

Sell

8,168 shares at $449.00

Nov 17, 2025$3.67M

Ausiello Dennis A

Director

Sell

7,675 shares at $435.40

Aug 14, 2025$3.34M

Ausiello Dennis A

Director

Sell

5,358 shares at $436.00

Aug 14, 2025$2.34M

Ausiello Dennis A

Director

Sell

5,302 shares at $439.27

Aug 14, 2025$2.33M

PYOTT DAVID E I

Director

Sell

7,440 shares at $299.00

Mar 24, 2025$2.22M

Institutional Ownership Analysis

Institutional ownership analysis with position momentum, 13F share flow, and ownership percentage trends.

Institutional Ownership Over Time for ALNY

Total dollar value invested by institutions each quarter

Neutral

Mixed institutional activity in Q1 2026

98.4% institutional ownership

Slight accumulation: 525 adding vs 431 reducing

13F share count essentially flat

Momentum weakening from prior quarter

Position Changes

Q2 2026: how are institutions adjusting their positions?

+164 growing-638 shrinkingNet: -474

136

558

New (28)

Increased (136)

Reduced (80)

Closed (558)

Top Institutional Holders, ALNY

Largest 8 institutional positions by ownership percentage as of Q2 2026

MASSACHUSETTS FINANCIAL SERVICES CO /MA/

350.6K

$105.5M

Ownership

0.26%

-29.3%

SUMITOMO MITSUI TRUST GROUP, INC.

325.4K

$97.9M

Ownership

0.24%

+3.5%

PICTET ASSET MANAGEMENT HOLDING SA

278.6K

$83.3M

Ownership

0.21%

+17.1%

CONGRESS ASSET MANAGEMENT CO /MA

265.7K

$80.0M

Ownership

0.20%

-7.0%

TD ASSET MANAGEMENT INC

233.7K

$70.3M

Ownership

0.18%

-17.1%

CITIGROUP INC

227.8K

$68.6M

Ownership

0.17%

-13.5%

ROBECO INSTITUTIONAL ASSET MANAGEMENT B.V.

188.1K

$56.6M

Ownership

0.14%

+48.7%

ASSENAGON ASSET MANAGEMENT S.A.

155.7K

$46.9M

Ownership

0.12%

+20.8%

ETF and Mutual Fund Holdings

ETF and mutual fund activity breakdown showing buying vs selling funds, top fund holders, and detailed holdings.

Fund Activity

Q2 2026: 208 ETFs and mutual funds reporting

71 buying48 sellingNet: +23

Buying (71)

Unchanged (89)

Selling (48)

Bullish Signal

Funds accumulating in Q2 2026

208 ETFs and mutual funds reporting

71 buying vs 48 selling (balanced)

Top Fund Holders, ALNY

Largest 1 ETF and mutual fund positions by shares held as of latest filing

PARNASSUS FUNDS

49.0K

Weight

5.07%

No change

Alnylam Pharmaceuticals, Inc.· ALNY

Holdings Analysis

Insider Trading Activity

1.3Transaction History500Real market purchases and sales onlyShow All Types

Institutional Ownership Analysis

2.4Detailed Holdings113Most recent institutional positions with changes and valuations

ETF and Mutual Fund Holdings

3.3Fund Holdings Details25Most recent ETF and mutual fund holdings with share counts and weights

Search stocks

Holdings Analysis

Insider Trading Activity

1.3Transaction History500Real market purchases and sales onlyShow All Types

Institutional Ownership Analysis

2.4Detailed Holdings113Most recent institutional positions with changes and valuations

ETF and Mutual Fund Holdings

3.3Fund Holdings Details25Most recent ETF and mutual fund holdings with share counts and weights