Summit Therapeutics Inc.· SMMT

🇺🇸 US · LargeBroad USNASDAQ

Healthcare Biotechnology Website

Price: $17.85
Day: +0.73%
Mkt Cap: $14.24B
52W Range: $12.07 – $29.23
Volume: 13.06M
Beta: -1.24

D55D FrameworkQuarterly Data

Holdings Analysis

Insider activity, institutional flows, and fund ownership.

Smart Money: 4.4 / 5 (Bullish), from 3 of 3 components
Institutions Q2 2026: 269 institutions hold; 158 added, 60 reduced

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Summit Therapeutics Inc.

SMMT|Healthcare|Biotechnology

Current price: $18

Smart Money

Dimension 5 of 5

Insider selling pace · Q2 2026

—

buy-only quarter

Seller breadth · Q2 2026

0 sellers

vs 0.0 avg per quarter

Institutional net breadth · Q2 2026

+121

218 adding vs 97 reducing

Institutional ownership · Q2 2026

17.6%

269 institutions

Insider Selling Pace

Each quarter's selling vs this stock's own trailing 6-quarter average

Light <0.5xRoutineElevated >1.5xHeavy >3xBuying

Institutional Positions

Institutions adding above the line, reducing below, net as a line

NewIncreasedReducedClosedNet

Largest Institutional Holders, Q2 2026

By reported market value, and how each moved in the quarter

Holder

Change

BAKER BROS. ADVISORS LP

32.8M

-10.2%

FMR LLC

10.0M

-7.8%

STATE STREET CORP

9.5M

+35.2%

BLACKROCK, INC.

9.5M

-1.6%

VANGUARD CAPITAL MANAGEMENT LLC

5.7M

+0.0%

UBS GROUP AG

5.2M

+41.7%

ETF & Fund Activity, Q2 2026

How the covering funds split between buying, holding and selling

54 buying82 unchanged22 selling

156 funds held SMMT in Q2 2026, holding 34.5M shares between them, down 6.6% on the quarter.

Largest fund holders

SPDR SERIES TRUST7.5M sh

NATIONWIDE MUTUAL FUNDS10.5K sh

Calvert Variable Products, Inc.9.6K sh

Notable Insider Transactions, Q2 2026

Largest open-market purchases and sales by value in the last eight quarters

Purchase · Jun 12

Zanganeh Mahkam

$50.0M

Purchase · Jun 12

DUGGAN ROBERT W

$50.0M

Purchase · Oct 21

Xia Yu

$10.0M

Insider transactions from SEC Form 4 filings; institutional holdings from quarterly 13F filings, which are reported with a lag and can overlap between filers. 13F: quarterly institutional holdings report · ETF: Exchange-Traded Fund

See the complete picture

The full 5D Framework: Business Quality · Peer Comparison · Valuation · Analyst Sentiment · Smart Money

Explore SMMT on stockoscope.com→

Generated September 20, 2026

For educational purposes only. Not financial advice. Data may be delayed or incomplete.

Smart Money Sentiment

SMMT Smart Money Sentiment Score

A weighted 1-5 sentiment score across three smart money signals.

Smart Money

4.4/5

Bullish

Weighted across 3 components

Component Breakdown (3 of 3 available)

Insider Activity

40% weight

+41

Institutional Flow

50% weight

+100

Fund Flow

10% weight

+60

Overall Smart Money sentiment of 4.4/5 (Bullish) based on a weighted combination of 3 components. Insider activity uses a relative-baseline comparison against the stock's own history; institutional flow tracks position momentum and 13F share changes; fund flow measures ETF / mutual-fund buying vs selling. Higher scores indicate stronger bullish sentiment from professional investors.Last updated September 19, 2026.

Insider Trading Activity

Insider trading analysis comparing the latest quarter against the stock's own historical baseline.

Insider Selling Pace for SMMT

Each quarter's selling vs the stock's own trailing 6-quarter average; 1.0x is typical for this stock. Green triangles mark quarters with insider buying.

Bullish Signal

Insider buying in Q2 2026

Major: 3 purchases totaling $51.8M (3.9M shares)

Limited history to compare against

Insider buying in 3 of the last 4 quarters

—

Selling pace

buy-only quarter

0.00%

Stake sold

of active insiders' holdings

0 sellers

Seller breadth

in Q2 2026

$51.8M

Insider buying

2 buyers in Q2 2026

Notable Recent Transactions, SMMT

Top 8 highest-value insider trades from the last 8 quarters

Zanganeh Mahkam

Co-Chief Executive Officer

Buy

3,810,000 shares at $13.12

≈0.7% of their stake after buying

Jun 12, 2026$49.99M

DUGGAN ROBERT W

Co-Chief Executive Officer

Buy

3,810,000 shares at $13.12

≈0.7% of their stake after buying

Jun 12, 2026$49.99M

Xia Yu

Director

Buy

533,617 shares at $18.74

≈1.7% of their stake after buying

Oct 21, 2025$10.00M

DUGGAN ROBERT W

Co-Chief Executive Officer

Buy

333,394 shares at $17.68

≈0.1% of their stake after buying

Sep 10, 2025$5.89M

Zanganeh Mahkam

Co-Chief Executive Officer

Buy

333,394 shares at $17.68

≈0.1% of their stake after buying

Sep 10, 2025$5.89M

DUGGAN ROBERT W

Co-Chief Executive Officer

Buy

100,000 shares at $14.60

≈0.4% of their stake after buying

Jun 4, 2026$1.46M

Zanganeh Mahkam

Co-Chief Executive Officer

Buy

100,000 shares at $14.60

≈0.4% of their stake after buying

Jun 4, 2026$1.46M

DUGGAN ROBERT W

Co-Chief Executive Officer

Buy

26,680 shares at $18.74

≈34.8% of their stake after buying

Oct 21, 2025$499.98K

Institutional Ownership Analysis

Institutional ownership analysis with position momentum, 13F share flow, and ownership percentage trends.

Institutional Positions for SMMT

Institutions adding (new + increased) above zero, reducing (reduced + closed) below, net as a line

New Increased Reduced Closed Net (adding − reducing)

Very Bullish

Institutions accumulating in Q2 2026

17.6% institutional ownership

Strong accumulation: 218 institutions adding vs 97 reducing positions

13F shares increased by 13.1%, a significant shift

Momentum improving from prior quarter

+121

Net breadth

218 adding vs 97 reducing

Strong accumulation

2.25

Add / reduce ratio

in Q2 2026

+23

New − closed

60 initiated, 37 exited

5 of 10

Top holders adding

largest holders with a known change

Position Changes

Q2 2026: how are institutions adjusting their positions?

+218 growing-97 shrinkingNet: +121

158

New (60)

Increased (158)

Reduced (60)

Closed (37)

Top Institutional Holders, SMMT

Largest 8 institutional positions by ownership percentage as of Q2 2026

BAKER BROS. ADVISORS LP

32.8M

$477.7M

Ownership

4.21%

-10.2%

FMR LLC

10.0M

$146.3M

Ownership

1.29%

-7.8%

STATE STREET CORP

9.5M

$139.0M

Ownership

1.23%

+35.2%

BLACKROCK, INC.

9.5M

$138.8M

Ownership

1.22%

-1.6%

VANGUARD CAPITAL MANAGEMENT LLC

5.7M

$83.6M

Ownership

0.74%

+0.0%

UBS GROUP AG

5.2M

$76.3M

Ownership

0.67%

+41.7%

VANGUARD PORTFOLIO MANAGEMENT LLC

5.0M

$73.5M

Ownership

0.65%

-4.0%

GOLDMAN SACHS GROUP INC

4.5M

$65.8M

Ownership

0.58%

+1347.4%

ETF and Mutual Fund Holdings

ETF and mutual fund activity breakdown showing buying vs selling funds, top fund holders, and detailed holdings.

Fund Activity

Q2 2026: 158 ETFs and mutual funds reporting

54 buying22 sellingNet: +32

Buying (54)

Unchanged (82)

Selling (22)

In total, funds bought 2.7M shares and sold 5.0M this quarter. Each fund counts once in the bar above, whatever the size of its move.

Very Bullish

Funds accumulating in Q2 2026

158 ETFs and mutual funds reporting

54 funds buying vs 22 selling

Top Fund Holders, SMMT

Largest 8 ETF and mutual fund positions by shares held, each fund's latest filing

SPDR SERIES TRUST

7.5M

Weight

36.86%

Jul 31, 2026No change

NATIONWIDE MUTUAL FUNDS

10.5K

Weight

0.00%

Jul 31, 2026No change

Calvert Variable Products, Inc.

9.6K

Weight

0.43%

Jun 30, 2026No change

Venerable Variable Insurance Trust

9.3K

Weight

0.02%

Jun 30, 2026No change

BlackRock Variable Series Funds, Inc.

8.7K

Weight

0.00%

Jun 30, 2026Increased

VANGUARD QUANTITATIVE FUNDS

7.9K

Weight

0.05%

Jun 30, 2026No change

FEDERATED HERMES INSURANCE SERIES

7.4K

Weight

0.20%

Jun 30, 2026No change

Legg Mason Global Asset Management Trust

5.0K

Weight

0.00%

Jun 30, 2026No change

Summit Therapeutics Inc.· SMMT

Holdings Analysis

Insider Trading Activity

1.3Transaction History42Real market purchases and sales onlyShow All Types

Institutional Ownership Analysis

2.4Detailed Holdings122Most recent institutional positions with changes and valuations

ETF and Mutual Fund Holdings

3.3Fund Holdings Details25Most recent ETF and mutual fund holdings with share counts and weights

Search stocks

Holdings Analysis

Insider Trading Activity

1.3Transaction History42Real market purchases and sales onlyShow All Types

Institutional Ownership Analysis

2.4Detailed Holdings122Most recent institutional positions with changes and valuations

ETF and Mutual Fund Holdings

3.3Fund Holdings Details25Most recent ETF and mutual fund holdings with share counts and weights